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Metabolic and Morphological Differences between Rapidly Proliferating Cancerous and Normal Breast Epithelial Cells

29 Feb 2008

Abstract excerpt

The metabolic and morphological characteristics of two human epithelial breast cell populations--MCF7 cells, a cancerous cell line, and 48R human mammary epithelial cells (48R HMECs), a noncancerous, finite lifespan cell strain--were compared at identical growth rates. Both cell types were induced to grow rapidly in nutrient-rich media containing 13C-labeled glucose, and the isotopic enrichment of cellular...

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PMID: 18307352
DOI: 10.1021/bp070301d

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