Article
Comparative study of topological indices of macro/supramolecular RNA complex networks.
Journal of chemical information and modeling - 1 Nov 2008
Agüero-Chapín Guillermín, Antunes Agostinho, Ubeira Florencio M, Chou Kuo-Chen, González-Díaz Humberto
Abstract excerpt
RNA function annotation is often based on alignment to a previously studied template. In contrast to the study of proteins, there are not many alignment-free methods to predict RNA functions if alignment fails. The use of topological indices (TIs) of RNA complex networks (CNs) to find quantitative structure-activity relationships (QSAR) may be an alternative to incorporate secondary structure or...
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