Article
Topological learning prediction of virus-like particle stoichiometry and stability.
Biophysical journal - 15 Sept 2026
Liu Xiang, Huang Xuefei, Wei Guo-Wei
Abstract excerpt
Understanding the stoichiometry and associated stability of virus-like particles (VLPs) is crucial for optimizing their assembly efficiency and immunogenic properties, which are essential for advancing biotechnology, vaccine design, and drug delivery. However, current experimental methods for determining VLP stoichiometry are labor intensive and time-consuming. Machine learning approaches have hardly been applied...
Read the complete abstract on PubMedTopics
- Machine Learning
- Virion
- Protein Stability
- Mutation
