Article
Genetic and biochemical determinants of serum concentrations of monocyte chemoattractant protein-1, a potential neural tube defect risk factor.
Birth defects research. Part A, Clinical and molecular teratology - 1 Oct 2008
Lu Zhi-Yong, Morales Megan, Khartulyari Stephanie, Mei Minghua, Murphy Kristen M, Stanislawska-Sachadyn Anna, Summers Carolyn M, Huang Yuehua, Von Feldt Joan M, Blair Ian A, Mitchell Laura E, Whitehead Alexander S
Abstract excerpt
BACKGROUND: Women with the AA genotype at the (-2518)A>G promoter polymorphism of CCL-2, which encodes the potent pro-inflammatory chemokine monocyte chemoattractant protein 1 (MCP-1), may be at increased risk for having offspring affected by spina bifida. As the A allele at this locus has been a...
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