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Article

Placental CCR5 polymorphisms in relation to fetal growth.

Journal of reproductive immunology - 1 Sept 2025

Wang Li Qing, Del Gobbo Giulia F, Wong Elizabeth, Wilson Samantha L, Campbell Mackenzie, Konwar Chaini, Peñaherrera Maria, Money Deborah, Côté Hélène, Robinson Wendy P

Abstract excerpt

The placenta mediates fetal growth, and its development and function are influenced by immune interactions at the maternal-fetal interface. The cysteine-cysteine chemotactic cytokine receptor type 5 (CCR5) gene codes for a pro-inflammatory protein receptor expressed in the placenta on syncytiotrophoblasts and Hofbauer cells. Associations of the placental-fetal genotype at CCR5 and birth outcomes have not been...

Read the complete abstract on PubMed

Topics

Humans
Female
Receptors, CCR5
Pregnancy
DNA Methylation
Placenta

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Fetal Development

Adult

Birth Weight

Genotype

HIV Infections

Alleles

Polymorphism, Genetic

Polymorphism, Single Nucleotide

Cohort Studies

Infant, Newborn

Source

Identifiers

PMID: 40706255
DOI: 10.1016/j.jri.2025.104622

Genes

CCR5
CCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

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