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Article

Self-assembled prodrugs: an enzymatically triggered drug-delivery platform.

Biomaterials - 1 Jan 2009

Vemula Praveen K, Cruikshank Gregory A, Karp Jeffrey M, John George

Abstract excerpt

Enzyme catalysis as a tool to disassemble supramolecular hydrogels to control the release of encapsulated drugs provides an opportunity to design a wide range of enzyme-specific low-molecular-weight hydrogelators. In this proof-of-concept work, we report the synthesis of low-molecular-weight amphiphilic prodrugs as hydrogelators from a well-known drug acetaminophen (which belongs to a class of drugs called...

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Identifiers

PMID: 18930313
DOI: 10.1016/j.biomaterials.2008.09.045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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