Article
The association of MMP-9 and IL-18 gene promoter polymorphisms with gingivitis in adolescents.
Archives of oral biology - 1 Feb 2009
Vokurka Jan, Klapusová Lucie, Pantuckova Pavla, Kukletova Martina, Kukla Lubomír, Holla Lydie Izakovicova
Abstract excerpt
OBJECTIVE: Interleukin 18 (IL-18) is shown to be a proinflammatory cytokine that regulates the expression of matrix metalloproteinase 9 (MMP-9). The aim of this study was to test for differences between Czech adolescents with and without gingivitis in relation to MMP-9 and IL-18 polymorphisms. DESIGN: A total of 298 Caucasian children, aged 11-13 years, were examined to assess gingival health. DNA for genetic...
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