Article
Functional polymorphisms in the matrix metalloproteinase-9 gene in relation to severity of chronic periodontitis.
Journal of periodontology - 1 Nov 2006
Holla Lydie Izakovicova, Fassmann Antonin, Muzík Jan, Vanek Jiri, Vasku Anna
Abstract excerpt
BACKGROUND: Members of the matrix metalloproteinase (MMP) family are implicated in the chronic remodeling in periodontal diseases. Therefore, we performed a case-control study to investigate a plausible association between susceptibility to chronic periodontitis (CP) and the polymorphisms in the MMP-9 (gelatinase B) gene. METHODS: Using polymerase chain reaction with subsequent restriction analyses, MMP-9...
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