Article
Characterization of the genetic switch from phage ɸ13 important for Staphylococcus aureus colonization in humans.
MicrobiologyOpen - 1 Oct 2021
Kristensen Camilla S, Varming Anders K, Leinweber Helena A K, Hammer Karin, Lo Leggio Leila, Ingmer Hanne, Kilstrup Mogens
Abstract excerpt
Temperate phages are bacterial viruses that after infection either reside integrated into a bacterial genome as prophages forming lysogens or multiply in a lytic lifecycle. The decision between lifestyles is determined by a switch involving a phage-encoded repressor, CI, and a promoter region from which lytic and lysogenic genes are divergently transcribed. Here, we investigate the switch of phage ɸ13 from the...
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