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Article

Moonlighting bacteriophage proteins derepress staphylococcal pathogenicity islands.

Nature - 10 Jun 2010

Tormo-Más María Angeles, Mir Ignacio, Shrestha Archana, Tallent Sandra M, Campoy Susana, Lasa Iñigo, Barbé Jordi, Novick Richard P, Christie Gail E, Penadés José R

Abstract excerpt

Staphylococcal superantigen-carrying pathogenicity islands (SaPIs) are discrete, chromosomally integrated units of approximately 15 kilobases that are induced by helper phages to excise and replicate. SaPI DNA is then efficiently encapsidated in phage-like infectious particles, leading to extremely high frequencies of intra- as well as intergeneric transfer. In the absence of helper phage lytic growth, the island...

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Identifiers

PMID: 20473284
DOI: 10.1038/nature09065
PMCID: PMC3518041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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