Article
Sequence variation in group A Streptococcus pili and association of pilus backbone types with lancefield T serotypes.
The Journal of infectious diseases - 15 Dec 2008
Falugi Fabiana, Zingaretti Chiara, Pinto Vittoria, Mariani Massimo, Amodeo Laura, Manetti Andrea G O, Capo Sabrina, Musser James M, Orefici Graziella, Margarit Immaculada, Telford John L, Grandi Guido, Mora Marirosa
Abstract excerpt
BACKGROUND: We previously reported that group A Streptococcus (GAS) pili are the T antigens described by Rebecca Lancefield. We also showed that these pili, constituted by backbone, ancillary 1, and ancillary 2 proteins, confer protection against GAS challenge in a mouse model. METHODS: We evalua...
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