Article
Relationship between the isoniazid-resistant mutation katGS315T and the prevalence of MDR-/XDR-TB in Osaka, Japan.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Nov 2008
Ano H, Matsumoto T, Suetake T, Nagai T, Tamura Y, Takamatsu I, Iwasaki T, Matsuoka H, Sasada S, Tetsumoto S, Tsuyuguchi I, Kusunoki Y, Takashima T
Abstract excerpt
OBJECTIVE: To determine the prevalence of katGS315T mutations in isoniazid (INH) resistant Mycobacterium tuberculosis and to elucidate the association of katGS315T mutations with the prevalence of multidrug-resistant tuberculosis (MDR-TB). DESIGN: From 2001 to 2004, 1655 isolates from all newly registered patients who visited the Osaka Prefectural Medical Centre for Respiratory and Allergic Diseases were tested...
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