Article
ADAM33, a new candidate for psoriasis susceptibility.
PloS one - 19 Sept 2007
Lesueur Fabienne, Oudot Tiphaine, Heath Simon, Foglio Mario, Lathrop Mark, Prud'homme Jean-François, Fischer Judith
Abstract excerpt
Psoriasis is a chronic skin disorder with multifactorial etiology. In a recent study, we reported results of a genome-wide scan on 46 French extended families presenting with plaque psoriasis. In addition to unambiguous linkage to the major susceptibility locus PSORS1 on Chromosome 6p21, we provided evidence for a susceptibility locus on Chromosome 20p13. To follow up this novel psoriasis susceptibility locus we...
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