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Article

Copy-Number Analysis of Topoisomerase and Thymidylate Synthase Genes in Frozen and FFPE DNAs of Colorectal Cancers

1 Oct 2008

Abstract excerpt

BACKGROUND: Archived formalin-fixed, paraffin-embedded specimens represent an important resource for pharmacogenomic analysis in retrospective clinical studies but the quality of results from formalin-fixed, paraffin-embedded samples is of concern due to the fact of the degradation of DNAs and RNAs from formalin-fixed, paraffin-embedded tissues. METHODS: In the present study, we used DNA from fresh frozen as well...

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Identifiers

PMID: 18855534
DOI: 10.2217/14622416.9.10.1459

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