Article
PPARgamma2 protects against obesity by means of a mechanism that mediates insulin resistance.
European journal of clinical investigation - 1 Nov 2009
Macias-Gonzalez M, Moreno-Santos I, García-Almeida J M, Tinahones F J, Garcia-Fuentes E
Abstract excerpt
BACKGROUND: Many studies have focused on the physiological parameters and genetic predisposition of subjects presenting both obesity and insulin resistance (IR) and it has been suggested that the peroxisome proliferator-activated receptor gamma 2 (PPARgamma2) Pro12Ala variant may contribute to the observed variability in insulin sensitivity. We investigated whether the PPARgamma2 mRNA expression levels are...
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