Article
Prevention of type 1 diabetes by immature dendritic cells treated with an ethanol extract of Paecilomyces hepiali Chen mycelium.
Methods and findings in experimental and clinical pharmacology - 1 Jan 2000
Zhang Chengliang, Zou Xiaolei, Leluo Guan, Xu Jing, Xiang Ming
Abstract excerpt
Dendritic cells (DCs) classically promote immune responses but can be manipulated to induce antigen-specific hyporesponsiveness. It has been shown that phenotypically "immature" DCs, defined by low levels of costimulatory molecules at the cell surface, are involved in the induction of peripheral immune tolerance in autoimmunity. Paecilomyces hepiali Chen (PHC) mycelium, as a substitute for Cordyceps, has been...
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