Article
Overlapping euchromatin/heterochromatin- associated marks are enriched in imprinted gene regions and predict allele-specific modification.
Genome research - 1 Nov 2008
Wen Bo, Wu Hao, Bjornsson Hans, Green Roland D, Irizarry Rafael, Feinberg Andrew P
Abstract excerpt
Most genome-level analysis treats the two parental alleles equivalently, yet diploid genomes contain two parental genomes that are often epigenetically distinct. While single nucleotide polymorphisms (SNPs) can be used to distinguish these genomes, it would be useful to develop a generalized strategy for identifying candidate genes or regions showing allele-specific differences, independent of SNPs. We have...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
