Article
Can we say that senescent cells cause ageing?
Experimental gerontology - 1 Jan 2000
Bird Joseph, Ostler Elizabeth L, Faragher Richard G A
Abstract excerpt
Replicative senescence, the irreversible loss of proliferative capacity, is a common feature of somatic cells derived from many different species. The molecular mechanisms controlling senescence in mammals, and especially in humans, have now been substantively elucidated. However, to date, attempts to link the senescence of cells with the ageing of the organisms they comprise has not met with any similar degree...
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