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Article

Identification of additional players in the alternative biosynthesis pathway to isovaleryl-CoA in the myxobacterium Myxococcus xanthus.

Chembiochem : a European journal of chemical biology - 5 Jan 2009

Bode Helge B, Ring Michael W, Schwär Gertrud, Altmeyer Matthias O, Kegler Carsten, Jose Ivy R, Singer Mitchell, Müller Rolf

Abstract excerpt

Isovaleryl-CoA (IV-CoA) is usually derived from the degradation of leucine by using the Bkd (branched-chain keto acid dehydrogenase) complex. We have previously identified an alternative pathway for IV-CoA formation in myxobacteria that branches from the well-known mevalonate-dependent isoprenoid biosynthesis pathway. We identified 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase (MvaS) to be involved in this...

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PMID: 18846531
DOI: 10.1002/cbic.200800219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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