Article
A better block partition and ligation strategy for individual haplotyping.
Bioinformatics (Oxford, England) - 1 Dec 2008
Zhao Yuzhong, Xu Yun, Wang Zhihao, Zhang Hong, Chen Guoliang
Abstract excerpt
MOTIVATION: Haplotype played an important role in the association studies of disease gene and drug responsivity over the past years, but the low throughput of expensive biological experiments largely limited its application. Alternatively, some efficient statistical methods were developed to deduce haplotypes from genotypes directly. Because these algorithms usually needed to estimate the frequencies of numerous...
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