Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An accurate clone-based haplotyping method by overlapping pool sequencing.

Nucleic acids research - 8 Jul 2016

Li Cheng, Cao Changchang, Tu Jing, Sun Xiao

Abstract excerpt

Chromosome-long haplotyping of human genomes is important to identify genetic variants with differing gene expression, in human evolution studies, clinical diagnosis, and other biological and medical fields. Although several methods have realized haplotyping based on sequencing technologies or population statistics, accuracy and cost are factors that prohibit their wide use. Borrowing ideas from group testing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Haplotypes
Share to Alleles
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosome Mapping

Share to Gene Expression

Share to Genetic Variation

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 27095193
DOI: 10.1093/nar/gkw284
PMCID: PMC4937318

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An accurate clone-based haplotyping method by overlapping pool sequencing.PMID 27095193Read ↗

On the design of clone-based haplotyping.Semantic proximity Read ↗

A Fosmid Pool-Based Next Generation Sequencing Approach to Haplotype-Resolve Whole Genomes.Semantic proximity Read ↗

Clone-based systematic haplotyping (CSH): a procedure for physical haplotyping of whole genomes.Semantic proximity Read ↗

Identifying rare variants with optimal depth of coverage and cost-effective overlapping pool sequencing.Semantic proximity Read ↗

Shotgun haplotyping: a novel method for surveying allelic sequence variation.Semantic proximity Read ↗

Integrating dilution-based sequencing and population genotypes for single individual haplotyping.Semantic proximity Read ↗

Fosmid-based whole genome haplotyping of a HapMap trio child: evaluation of Single Individual Haplotyping techniques.Semantic proximity Read ↗

Rare variant discovery and calling by sequencing pooled samples with overlaps.Semantic proximity Read ↗

Weighted pooling--practical and cost-effective techniques for pooled high-throughput sequencing.Semantic proximity Read ↗

De novo assembly of a haplotype-resolved human genome.Semantic proximity Read ↗

On optimal pooling designs to identify rare variants through massive resequencing.Semantic proximity Read ↗

Quantitative group testing-based overlapping pool sequencing to identify rare variant carriers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.