Article
HPV-16 E6 L83V variant in squamous cell carcinomas of the upper aerodigestive tract.
Journal of cancer research and clinical oncology - 1 Apr 2009
Boscolo-Rizzo Paolo, Da Mosto Maria Cristina, Fuson Roberto, Frayle-Salamanca Helena, Trevisan Rossana, Del Mistro Annarosa
Abstract excerpt
PURPOSE: The aim of this prospective case series study was to determine the prevalence of HPV-DNA, analyze the E6 mRNA expression, identify intra-type variation in the E6 oncogene in upper aerodigestive tract (UADT) squamous cell carcinoma (SCC), and correlate the presence of HPV-DNA with several clinical parameters and outcome. METHODS: Frozen samples of UADT-SCC were analyzed for the presence and...
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