Article
Human papillomavirus type 18 variant lineages in United States populations characterized by sequence analysis of LCR-E6, E2, and L1 regions.
Virology - 20 Jul 2005
Arias-Pulido Hugo, Peyton Cheri L, Torrez-Martínez Norah, Anderson D Nelson, Wheeler Cosette M
Abstract excerpt
While HPV 16 variant lineages have been well characterized, the knowledge about HPV 18 variants is limited. In this study, HPV 18 nucleotide variations in the E2 hinge region were characterized by sequence analysis in 47 control and 51 tumor specimens. Fifty of these specimens were randomly selected for sequencing of an LCR-E6 segment and 20 samples representative of LCR-E6 and E2 sequence variants were examined...
Topics
- Base Sequence
- Capsid Proteins
- Case-Control Studies
- DNA, Viral
- DNA-Binding Proteins
- Female
- Genetic Linkage
- Genetic Variation
- Humans
- Molecular Sequence Data
- Oncogene Proteins, Viral
- Papillomaviridae
- Papillomavirus Infections
