Article
Biological evidence for a causal role of HPV16 in a small fraction of laryngeal squamous cell carcinoma.
British journal of cancer - 9 Jul 2013
Halec G, Holzinger D, Schmitt M, Flechtenmacher C, Dyckhoff G, Lloveras B, Höfler D, Bosch F X, Pawlita M
Abstract excerpt
BACKGROUND: Human papillomavirus (HPV) is a causal factor in virtually all cervical and a subset of oropharyngeal squamous cell carcinoma (OP-SCC), whereas its role in laryngeal squamous cell carcinoma (L-SCC) is unclear. METHODS: Formalin-fixed paraffin-embedded (N=154) and deep-frozen tissues (N=55) of 102 L-SCC patients were analysed for the presence of 51 mucosal HPV types. HPV DNA-positive (HPV DNA+) cases...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
