Molecular basis for elliptocytosis associated with glycophorin C and D deficiency in the Leach phenotype.

Article

Molecular basis for elliptocytosis associated with glycophorin C and D deficiency in the Leach phenotype.

Blood - 15 Sept 1991

Telen M J, Le Van Kim C, Chung A, Cartron J P, Colin Y

Abstract excerpt

Glycophorin C (GPC) and glycophorin D (GPD) are highly glycosylated integral membrane proteins of human erythrocytes encoded by the same gene and associated with expression of Gerbich blood group system antigens. GPC/D deficiency (the Leach phenotype) is a rare condition usually found after ident...

Topics

Amino Acid Sequence
Blotting, Southern
Chromosome Deletion
Elliptocytosis, Hereditary
Exons
Glycophorins
Humans
Molecular Sequence Data
Mutation
Phenotype
RNA, Messenger

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