Article
Molecular basis for elliptocytosis associated with glycophorin C and D deficiency in the Leach phenotype.
Blood - 15 Sept 1991
Telen M J, Le Van Kim C, Chung A, Cartron J P, Colin Y
Abstract excerpt
Glycophorin C (GPC) and glycophorin D (GPD) are highly glycosylated integral membrane proteins of human erythrocytes encoded by the same gene and associated with expression of Gerbich blood group system antigens. GPC/D deficiency (the Leach phenotype) is a rare condition usually found after identification of Gerbich blood group system antibodies in persons undergoing prenatal or pretransfusion evaluation. In all...
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