Article
Prognostic significance of new immunohistochemistry scoring of p53 protein expression in cutaneous squamous cell carcinoma of mice.
Annals of the New York Academy of Sciences - 1 Sept 2008
Bukhari Mulazim Hussain, Niazi Shahida, Anwar Muhammad, Chaudhry Naseer Ahmed, Naeem Samina
Abstract excerpt
This study was conducted to investigate the prognostic value and therapeutic response of treatment modalities on p53 protein expression and AgNOR index in squamous cell carcinoma (SCC). Furthermore, based on data, we proposed a new p53 immunohistochemistry (IHC) scoring system. Sixty albino mice were given 7,12-dimethylbenz[a]anthracine (DMBA) and 12-O-tetradecanoly Phorbol-13-acetate (TPA) to produce skin...
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