Article
Clones of interstitial cells from bovine aortic valve exhibit different calcifying potential when exposed to endotoxin and phosphate.
Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2008
Rattazzi Marcello, Iop Laura, Faggin Elisabetta, Bertacco Elisa, Zoppellaro Giacomo, Baesso Ilenia, Puato Massimo, Torregrossa Gianluca, Fadini Gian Paolo, Agostini Carlo, Gerosa Gino, Sartore Saverio, Pauletto Paolo
Abstract excerpt
OBJECTIVE: Our purpose was to study in vitro whether phenotypically-distinct interstitial cell clones from bovine aortic valve (BVIC) possess different calcifying potential in response to endotoxin (lipopolysaccharide [LPS]) and phosphate (Pi). METHODS AND RESULTS: Among various clones of BVIC obtained by limited dilution technique we selected 4 clones displaying different growth patterns and immunophenotypes....
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