Article
Covalent binding of flavins to RnfG and RnfD in the Rnf complex from Vibrio cholerae.
Biochemistry - 28 Oct 2008
Backiel Julianne, Juárez Oscar, Zagorevski Dmitri V, Wang Zhenyu, Nilges Mark J, Barquera Blanca
Abstract excerpt
Enzymes of the Rnf family are believed to be bacterial redox-driven ion pumps, coupling an oxidoreduction process to the translocation of Na+ across the cell membrane. Here we show for the first time that Rnf is a flavoprotein, with FMN covalently bound to threonine-175 in RnfG and a second flavin bound to threonine-187 in RnfD. Rnf subunits D and G are homologous to subunits B and C of Na+-NQR, respectively....
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