Article
Role of the C-terminal tyrosine of ferredoxin-nicotinamide adenine dinucleotide phosphate reductase in the electron transfer processes with its protein partners ferredoxin and flavodoxin.
Biochemistry - 25 May 2004
Nogués Isabel, Tejero Jesús, Hurley John K, Paladini Darío, Frago Susana, Tollin Gordon, Mayhew Stephen G, Gómez-Moreno Carlos, Ceccarelli Eduardo A, Carrillo Néstor, Medina Milagros
Abstract excerpt
The catalytic mechanism proposed for ferredoxin-NADP(+) reductase (FNR) is initiated by reduction of its flavin adenine dinucleotide (FAD) cofactor by the obligatory one-electron carriers ferredoxin (Fd) or flavodoxin (Fld) in the presence of oxidized nicotinamide adenine dinucleotide phosphate (NADP(+)). The C-terminal tyrosine of FNR, which stacks onto its flavin ring, modulates the enzyme affinity for...
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