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Article

High-density SNP genotyping to define beta-globin locus haplotypes.

Blood cells, molecules & diseases - 1 Jan 2000

Liu Li, Muralidhar Shalini, Singh Manisha, Sylvan Caprice, Kalra Inderdeep S, Quinn Charles T, Onyekwere Onyinye C, Pace Betty S

Abstract excerpt

Five major beta-globin locus haplotypes have been established in individuals with sickle cell disease (SCD) from the Benin, Bantu, Senegal, Cameroon, and Arab-Indian populations. Historically, beta-haplotypes were established using restriction fragment length polymorphism (RFLP) analysis across the beta-locus, which consists of five functional beta-like globin genes located on chromosome 11. Previous attempts to...

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Source

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Identifiers

PMID: 18829352
DOI: 10.1016/j.bcmd.2008.07.002
PMCID: PMC4251776

Genes

SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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