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Article

Hemojuvelin N-terminal mutants reach the plasma membrane but do not activate the hepcidin response.

Haematologica - 1 Oct 2008

Pagani Alessia, Silvestri Laura, Nai Antonella, Camaschella Clara

Abstract excerpt

BACKGROUND: Hemojuvelin is a glycosylphosphatidylinositol-anchored protein, expressed in liver, skeletal muscle and heart. As a co-receptor of bone morphogenetic protein, membrane hemojuvelin positively modulates the iron regulator hepcidin. Mutations of the gene encoding for hemojuvelin cause ju...

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Identifiers

PMID: 18827264
DOI: 10.3324/haematol.12508

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18827264-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Hemojuvelin N-terminal mutants reach the plasma membrane but do not activate the hepcidin response.PMID 18827264Read ↗

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