Article
Impaired phenotype and function of monocyte derived dendritic cells in pulmonary tuberculosis.
Tuberculosis (Edinburgh, Scotland) - 1 Jan 2009
Rajashree P, Krishnan Gokula, Das Sulochana D
Abstract excerpt
Pulmonary tuberculosis (PTB) is often associated with impaired immunological functions. Blood monocytes, which can differentiate into dendritic cells upon cytokine stimulation, play a central role in adequate immune reactivity. Here, we investigated the morphologic, phenotypic and functional characteristics of in vitro-generated monocyte derived dendritic cells (MoDC) from PTB patients in comparison with healthy...
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