Article
Impairments of Antigen-Presenting Cells in Pulmonary Tuberculosis.
Journal of immunology research - 1 Jan 2015
Sakhno Ludmila V, Shevela Ekaterina Ya, Tikhonova Marina A, Nikonov Sergey D, Ostanin Alexandr A, Chernykh Elena R
Abstract excerpt
The phenotype and functional properties of antigen-presenting cells (APC), that is, circulating monocytes and generated in vitro macrophages and dendritic cells, were investigated in the patients with pulmonary tuberculosis (TB) differing in lymphocyte reactivity to M. tuberculosis antigens (PPD-reactive versus PPD-anergic patients). We revealed the distinct impairments in patient APC functions. For example, the...
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