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Diagnostic algorithm for identification of individuals with hereditary predisposition to breast cancer.

Likars'ka sprava - 1 Jan 2000

Hossein Rassi, Houshmand Massoud

Abstract excerpt

Breast cancer originates from genetic and environmental factors leading to accumulation of mutations in both nuclear DNA (nDNA) and mitochondrial DNA (mtDNA). Incidence of breast cancer cases rises dramatically with ageing. Approximately 90% of breast cancers are sporadic while the remaining 10% are inheritable. BRCA1 and BRCA2 mutations are associated with a greatly increased risk for development of hereditary...

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PMID: 18822852

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BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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