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Article

ABCB1 C1236T, G2677T/A and C3435T polymorphisms in systemic lupus erythematosus patients.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Sept 2008

Gonzalez T P, Mucenic T, Brenol J C T, Xavier R M, Schiengold M, Chies J A B

Abstract excerpt

P-glycoprotein (Pgp), the ABCB1 gene product, acts as an efflux pump that transports a large variety of substrates and is a mechanism of cell protection against xenobiotics. An increasing number of studies have shown that some ABCB1 polymorphisms may affect Pgp expression and activity, as well as affecting the development and susceptibility to diseases and pharmacological response. High activity of Pgp has been...

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Source

Identifiers

PMID: 18820766
DOI: 10.1590/s0100-879x2008000900005

Genes

ABCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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