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Article

Characterization of the Oxygen-Responsive NreABC Regulon of <i>Staphylococcus aureus</i>

27 Sept 2008

Abstract excerpt

Here, we investigate the functionality of the oxygen-responsive nitrogen regulation system NreABC in the human pathogen Staphylococcus aureus and evaluate its role in anaerobic gene regulation and virulence factor expression. Deletion of nreABC resulted in severe impairment of dissimilatory nitrate and nitrite reduction and led to a small-colony phenotype in the presence of nitrate during anaerobic growth. For...

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PMID: 18820014
DOI: 10.1128/jb.00905-08

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