Article
Possible difference in frequencies of genetic polymorphisms of estrogen receptor alpha, estrogen metabolism and P53 genes between estrogen receptor-positive and -negative breast cancers.
Japanese journal of clinical oncology - 1 Nov 2008
Hamaguchi Maho, Nishio Mariko, Toyama Tatsuya, Sugiura Hiroshi, Kondo Naoto, Fujii Yoshitaka, Yamashita Hiroko
Abstract excerpt
OBJECTIVE: Genetic polymorphisms associated with breast cancer risk are likely to differ among ethnic and molecular subtypes. The ability to identify genetic polymorphisms affecting the risk of estrogen receptor (ER)-positive breast cancer may lead to the more efficient selection of candidates for chemoprevention with endocrine agents. We focused on identifying common genotypes for ER-positive breast cancer in...
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