Article
Genetic variation may influence obesity only under conditions of diet: analysis of three candidate genes.
Molecular genetics and metabolism - 1 Nov 2008
Aberle Jens, Flitsch Jörg, Beck Nicola Alessia, Mann Oliver, Busch Philipp, Peitsmeier Philipp, Beil Frank Ulrich
Abstract excerpt
Under the hypothesis of obesity as a polygenetic disease numerous genes have been associated with an obese phenotype and metabolic co-morbidities. The cannabinoid receptor 1 (CB 1) is part of an underinvestigated system that participates in appetite control. Previous publications suggest that the endocannabinoid systems interact with the better understood leptin-melanocortin axis. Neuropeptide Y (NPY) is a player...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
