Role of genetic variation in the cannabinoid receptor gene (CNR1) (G1359A polymorphism) on weight loss and cardiovascular risk factors after liraglutide treatment in obese patients with diabetes mellitus type 2.

doi:10.2310/JIM.0000000000000032

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Article

Role of genetic variation in the cannabinoid receptor gene (CNR1) (G1359A polymorphism) on weight loss and cardiovascular risk factors after liraglutide treatment in obese patients with diabetes mellitus type 2.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Feb 2014

de Luis Daniel Antonio, Ovalle Hilda F, Soto Gonzalo Diaz, Izaola Olatz, de la Fuente Beatriz, Romero Enrique

Abstract excerpt

BACKGROUND: A polymorphism (1359 G/A) of the cannabinoid receptor 1 (CNR1) gene was reported as a common polymorphism (rs1049353) with potential implications in weight loss. We decide to investigate the role of this polymorphism on metabolic changes and weight loss secondary to treatment with liraglutide. METHODS: A population of 86 patients with diabetes mellitus type 2 and obesity, unable to achieve glycemic...

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Identifiers

PMID: 24322329
DOI: 10.2310/JIM.0000000000000032

Genes

CNR1

Variants

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