Article
UL40 human cytomegalovirus variability evolution patterns over time in renal transplant recipients.
Transplantation - 27 Sept 2008
Garrigue Isabelle, Faure-Della Corte Muriel, Magnin Noël, Recordon-Pinson Patricia, Couzi Lionel, Lebrette Marie-Elise, Schrive Marie-Hélène, Roncin Loïc, Taupin Jean-Luc, Déchanet-Merville Julie, Fleury Hervé, Lafon Marie-Edith
Abstract excerpt
BACKGROUND: Human cytomegalovirus (HCMV) is the most common opportunistic pathogen infecting immunocompromised patients after transplantation. Although its immunomodulatory capacities and genomic variability participate in immune system evasion, they are poorly studied in clinical strains without culture amplification. One of HCMV immunomodulatory genes, UL40, confers HCMV-infected cells' protection from natural...
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