Article
Variability and recombination of clinical human cytomegalovirus strains from transplantation recipients.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Feb 2010
Faure-Della Corte Muriel, Samot Johan, Garrigue Isabelle, Magnin Noël, Reigadas Sandrine, Couzi Lionel, Dromer Claire, Velly Jean-François, Déchanet-Merville Julie, Fleury Hervé J A, Lafon Marie-Edith
Abstract excerpt
BACKGROUND: Human cytomegalovirus (HCMV) is the first cause of viral infection in immunocompromised transplanted patients. OBJECTIVES: Here, five HCMV genes were studied to investigate the existence of recombination events in clinical strains ex vivo. STUDY DESIGN: Sequencing and phylogenetic analysis were conducted on 21 strains from 16 renal and 5 lung transplant recipients. RESULTS: Nucleotidic polymorphism...
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