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Article

Epigenetics as the mediator of fetal programming of adult onset disease: what is the evidence?

17 May 2014

Abstract excerpt

The Developmental Origins of Health and Disease hypothesis describes how early life environmental factors influence development in a way that impacts later health and disease risk. The hypothesis is supported by a large number of animal studies and a smaller number of observational studies in humans. Epigenetic variation induced in early life has emerged as a prime candidate to be the mediator of such effects,...

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PMID: 24835110
DOI: 10.1111/aogs.12431

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