Epigenetic gene regulation: linking early developmental environment to adult disease.

doi:10.1016/j.reprotox.2006.08.012

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Article

Epigenetic gene regulation: linking early developmental environment to adult disease.

Reproductive toxicology (Elmsford, N.Y.) - 1 Jan 2000

Dolinoy Dana C, Weidman Jennifer R, Jirtle Randy L

Abstract excerpt

Traditional studies on the combined effects of genetics and the environment on individual variation in disease susceptibility primarily focus on single nucleotide polymorphisms that influence toxicant uptake and metabolism. A growing body of evidence, however, suggests that epigenetic mechanisms...

Topics

Animals
Environmental Exposure
Epigenesis, Genetic
Gene Expression Regulation, Developmental
Genetic Predisposition to Disease
Humans

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