Article
Annexin A1 regulates intestinal mucosal injury, inflammation, and repair.
Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 2008
Babbin Brian A, Laukoetter Mike G, Nava Porfirio, Koch Stefan, Lee Winston Y, Capaldo Christopher T, Peatman Eric, Severson Eric A, Flower Roderick J, Perretti Mauro, Parkos Charles A, Nusrat Asma
Abstract excerpt
During mucosal inflammation, a complex array of proinflammatory and protective mechanisms regulates inflammation and severity of injury. Secretion of anti-inflammatory mediators is a mechanism that is critical in controlling inflammatory responses and promoting epithelial restitution and barrier recovery. AnxA1 is a potent anti-inflammatory protein that has been implicated to play a critical immune regulatory...
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