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Ace Deficiency Induces Intestinal Inflammation in Zebrafish

21 May 2024

Abstract excerpt

Inflammatory bowel disease (IBD) is a nonspecific chronic inflammatory disease resulting from an immune disorder in the intestine that is prone to relapse and incurable. The understanding of the pathogenesis of IBD remains unclear. In this study, we found that ace (angiotensin-converting enzyme), expressed abundantly in the intestine, plays an important role in IBD. The deletion of ace in zebrafish caused...

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PMID: 38891786
DOI: 10.3390/ijms25115598

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