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Article

Quantitative Mass Spectrometry Identifies Drug Targets in Cancer Stem Cell-Containing Side Population

18 Sept 2008

Abstract excerpt

A multifaceted approach is presented as a general strategy to identify new drug targets in a breast cancer stem cell-containing side population. The approach we have utilized combines side population cell sorting and stable isotope labeling by amino acids in cell culture with mass spectrometry to compare and identify proteins with differential expression profiles between side population cells, know to be enriched...

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PMID: 18802034
DOI: 10.1634/stemcells.2008-0397

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