Article

Huaier Polysaccharides Targets Cancer Stem Cells in Triple-Negative Breast Cancer via ASM-mediated Autophagy-dependent Ferroptosis

2024-12-30

Abstract excerpt

<title>Abstract</title> <p>Background Breast cancer stem cells (BCSCs) is critical in multiple progression of triple-negative breast cancer (TNBC). The iron concentration has been found to be higher in BCSCs. The inhibition of ferroptosis is conducive to maintaining the stemness of tumor stem cells. Despite preliminary reports indicating the effectiveness of (polysaccharides of Huaier) PS-T in the treatment of T...

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Literature Corpus work: 11328558-7a59-5c38-8e0a-6e896560d0aa
DOI: 10.21203/rs.3.rs-5706155/v1

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