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Article

BK Virus-Specific T Cell Response Associated with HLA Genotypes, RhD Status, and CMV or EBV Serostatus in Healthy Donors for Optimized Cell Therapy.

Journal of clinical immunology - 19 Jun 2025

Mora-Buch Rut, Tomás-Marín Maria, Pasamar Helena, Enrich Emma, Peña-Gómez Cleofé, Rudilla Francesc

Abstract excerpt

PURPOSE: The increasing application of virus-specific T cell therapy for treating BK virus infections in immunocompromised patients highlights the necessity for rapid identification of compatible cell donors with optimal BK-specific T cell response. This study aims to characterize the BK virus-specific T cell response in relation to demographic factors, blood group, serological status, and HLA genotypes using...

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Identifiers

PMID: 40537681
DOI: 10.1007/s10875-025-01901-2
PMCID: PMC12179236

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LTA

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