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Article

The effects of prion protein proteolysis and disaggregation on the strain properties of hamster scrapie.

The Journal of general virology - 1 Oct 2008

Deleault Andrea M, Deleault Nathan R, Harris Brent T, Rees Judy R, Supattapone Surachai

Abstract excerpt

Native mammalian prions exist in self-propagating strains that exhibit distinctive clinical, pathological and biochemical characteristics. Prion strain diversity is associated with variations in PrP(Sc) conformation, but it remains unknown precisely which physical properties of the PrP(Sc) molecu...

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Identifiers

PMID: 18796735
DOI: 10.1099/vir.0.2008/002303-0
PMCID: PMC2675185

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18796735-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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