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Article

Quantitative trait loci affecting phenotypic variation in the vacuolated lens mouse mutant, a multigenic mouse model of neural tube defects.

Physiological genomics - 12 Nov 2008

Korstanje Ron, Desai Jigar, Lazar Gloria, King Benjamin, Rollins Jarod, Spurr Melissa, Joseph Jamie, Kadambi Sindhuja, Li Yang, Cherry Allison, Matteson Paul G, Paigen Beverly, Millonig James H

Abstract excerpt

The vacuolated lens (vl) mouse mutant arose spontaneously on the C3H/HeSn background and exhibits neural tube defects (NTDs), congenital cataract, and occasionally a white belly spot. We previously reported that 1) the vl phenotypes are due to a mutation in an orphan G protein-coupled receptor (G...

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Identifiers

PMID: 18796533
DOI: 10.1152/physiolgenomics.90260.2008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18796533-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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